Table 1 Demographics and characteristics of severe COVID-19 patients in 1-year follow-up
Variables | Follow-up after 1Â year | |||
|---|---|---|---|---|
Total patients (n = 25) | hUC-MSCs (n = 8) | Control (n = 17) | P value# | |
Age, years, median (IQR) | 51.00 (45.00,67.00) | 50.50 (39.00, 72.75) | 52.00 (45.00,63.00) | 0.521 |
Male | 11 (44.00%) | 4 (50.0%) | 7 (41.18%) | 1.000 |
Smokers | 7 (28.00%) | 3 (37.5%) | 4 (23.53%) | 0.640 |
Body mass index (BMI) | 26.08 (22.16,27.99) | 22.91 (20.40, 24.43) | 26.08 (21.51,27.99) | 0.181 |
Diabetes/hypertension | 10 (40.00%) | 4 (50.0%) | 6 (35.29%) | 0.667 |
Blood routine examination | ||||
WBC, median (IQR), 109 /L | 5.60 (4.79,6.07) | 5.62 (4.98,6.27) | 5.60 (4.73,6.07) | 0.813 |
NEU, 109 /L | 3.24 (2.65,3.84) | 3.05 (2.24,4.15) | 3.27 (2.65,3.76) | 0.979 |
LYM, 109 /L | 1.76 (1.42,2.02) | 1.77 (1.26,2.02) | 1.76 (1.49,2.02) | 0.543 |
MON, 109 /L | 0.31 (0.22,0.45) | 0.26 (0.20,0.47) | 0.31 (0.26,0.45) | 0.776 |
HB, g/L | 143.00 (130.00,156.00) | 152.50 (128.75,162.50) | 141.00 (130.00,152.50) | 0.233 |
PLT, 109 /L | 227.00 (200.50,259.50) | 243.00 (194.75,261.75) | 226.00 (200.50,264.50) | 0.745 |
Blood biochemistry | ||||
AST, U/L | 21.00 (16.50,25.00) | 22.50 (15.00,32.00) | 21.00 (18.00,23.50) | 0.400 |
ALT, U/L | 21.00 (14.00,30.00) | 27.50 (19.25,36.25) | 20.00 (13.50,24.00) | 0.286 |
K, mmol/L | 4.23 (3.98,4.47) | 4.40 (4.27,4.77) | 4.08 (3.92,4.37) | 0.143 |
Na, mmol/L | 142.10 (140.45,142.70) | 141.05 (139.63,142.10) | 142.30 (141.30,142.95) | 0.141 |
Cl, mmol/L | 107.30 (105.55,108.80) | 106.40 (104.35,107.68) | 108.00 (106.20,109.30) | 0.135 |
BUN, mmol/L | 4.26 (3.96,5.64) | 4.07 (3.46,5.07) | 5.19 (4.05,6.09) | 0.132 |
Cr, μmol/L | 66.00 (56.50,80.00) | 60.50 (55.50,80.75) | 67.00 (58.50,83.00) | 0.484 |
Myocardial injury markers | ||||
CK | 107.00 (75.50,143.50) | 99.00 (76.50,171.25) | 107.00 (74.00,134.50) | 0.786 |
CK-MB | 1.83 (1.20,2.01) | 1.72 (1.16,2.23) | 1.83 (1.20,1.97) | 0.384 |
LDH | 175.00 (171.00,194.75) | 172.00 (166.00,218.00) | 176.00 (171.00,191.00) | 0.238 |
Blood coagulation | ||||
PT | 10.50 (10.25,10.75) | 10.50 (10.33,10.78) | 10.50 (10.15,10.75) | 0.316 |
APTT | 32.90 (29.55,34.75) | 33.45 (29.08,34.98) | 32.60 (29.55,35.00) | 0.926 |
D-Dimer | 0.06 (0.04,0.12) | 0.06 (0.04,0.26) | 0.06 (0.04,0.12) | 0.217 |
Inflammatory markers | ||||
CRP | 0.85 (0.61,1.72) | 0.86 (0.58,2.80) | 0.81 (0.63,1.39) | 0.152 |
PCT | 0.05 (0.05,0.05) | 0.05 (0.05,0.05) | 0.05 (0.05,0.05) | 0.149 |