Fig. 2

Change in ISNCSCI motor score. The change in the ISNCSCI upper extremity motor score A was 4.2 [1.0–7.4] (adjusted mean [95% CI]) at 4 weeks posttreatment (p = 0.016), 8.3 [5.3–11.2] at 12 weeks (p < 0.001), 8.4 [3.9–12.9] at 28 weeks (p = 0.002), and 8.3 [2.7–14.0] at 52 weeks (p = 0.009), showing statistically significant improvements at each time point compared to those data at the time of CL2020 administration. The change in the ISNCSCI lower extremity motor score B showed significant improvement at 4 weeks post-treatment (p < 0.05) but did not show statistically significant improvements after subsequent time points compared to the time of CL2020 administration. The changes in the total ISNCSCI motor score C were 7.7 [1.7–13.6] (p = 0.020), 13.6 [4.3–22.9] (p = 0.009), 14.8 [3.5–26.0] (p = 0.016), and 15.4 [2.3–28.5] (p = 0.026) at 4, 12, 24, and 52 weeks posttreatment, respectively, with statistically significant improvements at each time point compared to the time of CL2020 administration