Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: miR-340-3p-modified bone marrow mesenchymal stem cell-derived exosomes inhibit ferroptosis through METTL3-mediated m6A modification of HMOX1 to promote recovery of injured rat uterus

Fig. 2

MB-exos promote recovery of the injured uterus through the inhibition of ferroptosis. A Heatmap displaying the DEGs between the PBS and MB-exos groups (n = 3). B DEGs were evaluated with KEGG analysis, and 20 significantly enriched pathways are presented. C Transmission electron microscopy images showing mitochondrial morphology in the endometrium of different groups (Sham, PBS, B-exos, and MB-exos) (n = 3/group). D–G Assay results for MDA production, GSH depletion, iron accumulation, and GSSG levels in each group (Sham, PBS, B-exos, and MB-exos) [n.s.: not significant, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001] (n = 6/group). H Representative images of hematoxylin and eosin (HE)-stained uterus tissues from the Sham, PBS, MB-exos, and MB-exos + erastin groups (n = 6/group)

Back to article page