Fig. 3

Histologic sections analysis of effects of ADSCs on CRD skin regeneration. (A) (Left) photomicrographs of H&E-stained sections, 0week, 4 weeks and 8 weeks post treatment. Scare bar = 100 μm. (Right) photomicrographs of Masson-stained sections, 0week, 4 weeks and 8 weeks post treatment. Scare bar = 250 μm. (B) photomicrographs of Picrosirius red-stained sections, 0week, 4 weeks and 8 weeks post treatment. The green color indicates collagen III, while the yellow color indicates collagen I. Scare bar = 200 μm. (C-E) Statistical comparison of epidermis thickness (C), relative collagen density (D) and the ratio of Collagen III/Collagen I (E) between HA treatment and ADSCs treatment at different time points post injection. *p < 0.05; **p < 0.01; *** p < 0.001