Fig. 3
Cell engraftment and COL6 supplementation in the TA muscles of Col6a1-KO/NSG 12 weeks after cell transplantation. a Representative sectional images of the entire TA muscle at 12 weeks after cell transplantation. b–d Quantitative data on the percentage of COL6-positive area (b), percentage of COL6-positive fibers (c), and number of hLamin A/C (d) 12 weeks after transplantation. Data are shown as the mean ± SD. e Band graph representing the percentage of each muscle fiber size classified by diameter at 12 weeks after transplantation. Blue, 56 μm ≤ CSA short axis; yellow, 26 μm ≤ CSA short axis ≤ 55 μm; light green, CSA short axis ≤ 25 μm. f Average CSA of a single myofiber in the TA muscles. Data are shown as the mean ± SD. *p < 0.05; n = 12 (Ad-MSCs), n = 9 (BM-MSCs), n = 11 (XF-iMSCs), n = 27 (medium), n = 6 (WT)