Fig. 6

Cell therapy reduced the predicted cardiac adverse effects. A Ingenuity Pathway Analysis (IPA) identified 42 cardiac disease associations in the PAB-altered RV proteome. Further IPA of the reversed sub-proteomes from the cell therapy groups predicted reversal of many of these disease associations by MSC (B), nCPC (C), or ES-CPC (D) therapies. Black bars represent PAB vs CTL, red bars represent cell therapy fully and partially reversed sub-proteomes. Dashed lines in B-D indicate significance level of p = 0.05