Fig. 8

Cell therapies are retained in the heart and can affect RV function. A Summary time course of fluorescence in PAB rat hearts injected with DiR‐labeled MSCs, cCPCs, nCPCs, or ES-CPCs. Values are normalized to day 0 fluorescence values and plotted as percentage. Data are presented as individual values. *, p ≤ .05 vs. cCPC. B Summary time course data of tricuspid annular plane systolic excursion (TAPSE) measurements in experimental animal cohorts. Animal cohorts are identified as CTL (Sham, n = 4), PAB (banded, saline injected, n = 4), MSC (PAB + MSC injection, n = 3), nCPC (PAB + nCPC injection, n = 4), cCPC (PAB + cCPC injection, n = 4), or ES-CPC (PAB + ES-CPC injection, n = 4). All animals underwent PAB surgery at Day -14 and cell therapy cell populations were injected into the RV free wall 2 weeks post‐PAB (Day 0). Echocardiography was performed biweekly from Day -14. Data are presented as individual values. *, p ≤ .05 vs. PAB