Fig. 2

Spiking activity characterization during the chemical modulation. a–i Normalized Instantaneous Firing Rate (IFR) of 100E (red), 75E25I (orange), and 100I (blue) configurations when APV (first row), CNQX (second row), or BIC (third row) were used. The timepoint “Spont” represents the normalized firing rate computed over the 10-min recording of the spontaneous activity. Data are represented with the mean (dot) and the standard error of the mean (whiskers) (∗ refers to p < 0.05)