Fig. 7

Characterization of PTX e PTZ effects. a–c Normalized Instantaneous Firing Rate (IFR) over time of the 100E (red), 75E25I (orange), and 100I (blue) configurations when PTX was used. d–f Normalized IFR over time of the 100E (red), 75E25I (orange), and 100I (blue) configurations when PTZ was used. g–h Normalized Network Bursting Rate (NBR) over time of the 100E (red) and 75E25I (orange) configurations in the presence of PTX. Insets: Normalized number of network bursting units of the configurations in the spontaneous and PTX evoked conditions. i Normalized Network Burst Duration (NBD) of the 100E (left) and 75E25I (right) configurations in spontaneous (grey) and PTX evoked conditions (red and orange, respectively). j–k Normalized Network Bursting Rate (NBR) over time of the 100E (red) and 75E25I (orange) configurations in the presence of PTZ. Insets: Normalized number of network bursting units of the configurations in the spontaneous and PTZ evoked conditions. l Normalized Network Burst Duration (NBD) of the 100E (left) and 75E25I (right) configurations in spontaneous (grey) and PTZ evoked conditions (red and orange, respectively). Scatter plots are represented with the mean (dot) and the standard error of the mean (whiskers). Box plots are represented with the percentile 25–75 (box), the standard deviation (whiskers), the median (line), the mean (square), and the minimum and maximum (crosses) values (∗ refers to p < 0.05)