Fig. 3

Identification of interpopulation differences in ADRC populations between responders and non-responders. A Heatmap visualizing all differentially expressed genes in an intra cell type (as defined by UMAP in Fig. 2G) comparison between responders and non-responders (Wilcox ranksum test, adj. p value < 0.05, FC > 1.1). Heatmap is scaled and arranged by p value. B Quantification of differentially expressed genes for each cell type. C Expression levels of genes related to secretion from each identified cell population. Genes are retrieved from The Human Protein Atlas (proteinatlas.org), and Gene Ontology terms