Fig. 2

hUC-MSCs can alleviate renal interstitial fibrosis and renal senescence after AKI. A Schematic diagram of treatment. hUC-MSCs were mixed with collagen matrix and given to uIRI mice for two doses. Model group mice were injected with rat tail collagen. Kidneys were harvested at 14 days post-uIRI for analysis (n = 6 mice per group). B Immunohistological staining images of Masson staining. Scale bar, 20 μm. C Immunohistological staining images of SA-β-gal. Scale bar, 20 μm. D Western blotting of senescence indicators. E Quantification of senescence indicators. Data are presented as mean ± SD. **P < 0.01; *P < 0.05. ns, not significant