Fig. 4

Histological analysis of mandibular advancement combined with SCAP injection effects in the rat model. A- A1 HE stains (7 × Visual 100x) and area ratio analysis of rat condylar cartilage after 4 weeks of MA, 8 weeks of MA, and SCAPs injection. B- B1 Safranin-Fast Green staining (7 × Visual 100x) and area ratio analysis of rat condylar cartilage after 4 weeks of MA, 8 weeks of MA, and SCAPs injection. (*: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: not statistically significant). C- C1 HE stains (7 × Visual 100x) and area ratio analysis of rat condylar cartilage under different SCAPs injection frequencies. D- D1 Safranin-Fast Green staining (7 × Visual 100x) and area ratio analysis of rat condylar cartilage under different SCAPs injection frequencies. (***: compared with Control group, p < 0.001; ◇◇: Compared with MA group, p < 0.01; ◇◇◇: Compared with MA group, p < 0.001; ns: not statistically significant). Scale bar = A, B, C, D is 100 μm