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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Using magnetic resonance relaxometry to evaluate the safety and quality of induced pluripotent stem cell-derived spinal cord progenitor cells

Fig. 2

Difference in iPSCs and SCPCs intracellular iron levels allows MRR to pick up varying levels of iPSCs in SCPCs via T2 measurements A Fe3+ fluorescent intensity of iPSCs and SCPCs analyzed via FACS showed a significant difference in Fe3 between the 2 cell types. B T2 values of SCPCs were significantly higher than iPSCs. C Schematic of artificial spiking of iPSCs in SCPCs at 1%, 5% and 10% concentrations to alter SCPC T2 measurements. D Decrement of T2 values with increasing spiked iPSC concentration at 1%, 5% and 10% (n = 4). Statistical significance was determined by a Mann–Whitney u-test

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