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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Impact of mesenchymal stem cell size and adhesion modulation on in vivo distribution: insights from quantitative PET imaging

Fig. 2

Effects of cell adhesion capacity on hUC-MSCs distribution in vivo. (A) Representative PET images of BALB/c mice injected with 89Zr-labeled hUC-MSCs at various time point within 48 h. The hUC-MSCs were pre-incubated with RGD, GFOGER, HAVDI and PBS as a control before radiolabeling. (B) Lung uptake of the 89Zr-labeled hUC-MSCs based on the PET imaging (n = 3). (C) Ex vivo biodistribution of intravenously transplanted 89Zr-labeled MSCs in BALB/c mice (n = 3). Values are expressed as the means ± SD. *, p < 0.05; ns, not significant, p > 0.05

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