Fig. 5

RNA-Seq analysis revealed significantly decreased Wnt signaling components and TGF-beta signaling pathway in Epi-GMSCs. (A) Volcano plot indicating the total number of genes differentially up-regulated and down-regulated. (B) Heat map generated from gene expression array of Wnt signaling pathway and TGF-beta signaling pathway-related genes. (C) GO and (D) KEGG analysis of RNA-Seq data showing downregulation of Wnt signaling pathway in GMSCs after 9 days of incubation in GECCM. (n = 3)