Fig. 4

Improvement of ovarian function of mice treated with CTX by HF-MSCs & HU-MSCs transplantation. A, B, C The hormone levels of AMH, FSH, E2 were measured by ELISA on 2 weeks after the last transplantation of MSCs of each group. The error bars indicate SD (n = 6). D Each follicle type per ovary. AF, antral follicle; AtF, atretic follicle; SF, secondary follicle; PF, primary follicle; PdF, primordial follicle (n = 3). E Ovarian histology was analyzed 2 weeks after the last transplantation of MSCs using H&E staining (n = 3). *: p < 0.05, **: p < 0.01, ***: p < 0.001, and ns: no significance. Scale bar = 200 or 500 μm