Fig. 6

The changes in serum oxidative stress indexes and mitochondrial structure after HF-MSCs transplantation. A The serum concentration of ROS, MDA, SOD were measured by ELISA, and Fe2+ were measured by chemiluminescence on 2 weeks after the last transplantation of MSCs of each group. The error bars indicate SD (n = 6). B Representative image of mitochondrial ultramicro structure from the granulosa cells of primary follicles detected by TEM (yellow arrow: long rod-like structures; red arrow: vacuolization; green arrow: mitochondrial cristae; blue arrow: globular bodies, blurred membranes) (n = 1). Data represent mean ± SD; *: p < 0.05, **: p < 0.01, and ns: no significance. Scale bar: 5 μm (original), 1 μm (enlarged)