Table 1 Characteristics of the NCR and CCR groups
Characteristics | CCR group (N = 118) | NCR group (N = 88) | p |
|---|---|---|---|
Age, median (range) [years] | 4(3,7) | 7(4,10) | < 0.001 |
Sex | |||
Male, n (%) | 84(71.2) | 54(61.4) | 0.138 |
Female, n (%) | 34(28.8) | 34(38.6) | |
Serum ferritin, median (range) [µg/L] | 1802.0(1254.0,2689.5) | 2113.5 (1199.5, 2700.8) | 0.552 |
Risk group, n (%) | (N = 116) | (N = 88) | |
Low-risk | 30(25.9) | 13((14.8) | 0.019 |
Medium-risk | 86(74.1) | 72 (81.8) | |
High-risk | 0(0) | 3(3.4) | |
Donor/patient ABO-match, n (%) | |||
Match | 75(63.6) | 41(46.6) | 0.015 |
Mismatch | 43(36.4) | 47 (53.4) | |
PRA before, n (%) | [N = 89] | [N = 70] | |
Negative (≤ 10%) | 52(58.4) | 42 (60.0) | 0.018 |
Positive (11–29%) | 25(28.1) | 9(12.9) | |
Strongly positive (≥ 30%) | 12(13.5) | 19(27.1) | |
Donor source, n (%) | |||
Matched sibling donor | 65(55.1) | 28(31.8) | |
Unrelated donor | 53(44.9) | 60(68.2) | |
HLA matching status, n (%) | |||
10/10 matched | 99(83.9) | 60(68.2) | |
9/10 matched | 16(13.6) | 26(29.5) | |
8/10 matched | 3(2.5) | 2(2.3) | |
Stem cell source, n (%) | |||
BM | 2(1.7) | 0 | |
PBSC | 51(43.2) | 60(68.2) | |
UCB | 1(0.8) | 0 | |
BM + PBSC | 50(42.4) | 17(19.3) | |
BM + UCB | 8(6.8) | 5(5.7) | |
PBSC + UCB | 2(1.7) | 0 | |
BM + PBSC + UCB | 4(3.4) | 6(6.8) | |
Follow-up, median (range) [months] | 46.3(24.7,68.6) | 46.0(25.0,52.6) |