Table 3 The change of immune status under immunosuppressive therapy before transplantation
Variables, median(range) | before FD | after FD | p |
|---|---|---|---|
PRA titers (%)(N = 28) | 22.5(3.3–54.5) | 11.5(0-37.3) | 0.002 |
Class I HLA | 19.5(2.5–41.0) | 7.5(0–31.0) | 0.003 |
Class II HLA | 0(0-15.5) | 0(0-1.8) | 0.043 |
Lymphocyte subsets (N = 46) | |||
WBC (×109/L) | 6.4(4.4, 8.6) | 3.3(2.3, 5.0) | < 0.001 |
LYM (×109/L) | 2.5(1.9, 3.6) | 0.6(0.5, 1.0) | < 0.001 |
TCL (cells/uL) | 1746.7(1370.7, 2147.3) | 521.0(337.9, 782.4) | < 0.001 |
BCL (cells/uL) | 501.4(289.9, 900.2) | 35.8(8.3, 112.2) | < 0.001 |
NK (cells/uL) | 218.8(163.6, 358.8) | 84.4(54.9, 112.5) | < 0.001 |
CD3 + CD4+ (cells/uL) | 827.7(650.2, 1068.1) | 231.6(158.1, 370.6) | < 0.001 |
CD3 + CD8+ (cells/uL) | 662.2(489.9, 899.1) | 217.8(142.8, 308.2) | < 0.001 |
CD4+/CD8+ | 1.14(0.95, 1.50) | 1.20(0.88, 1.62) | 0.701 |