Fig. 4

Source data are available in the Source Data file
Consistent alterations in cellular processes. a GSEA analysis of up-regulated and down-regulated pathways in P6 MSCs compared to P2 MSCs (x-axis) and in P10 MSCs compared to P6 (y-axis), based on GO subset in AmiGO database. Normalized enrichment scores (NES) of GO terms are plotted. b Quantitative analysis of altered pathways across different passages of MSCs based on GSEA analysis. (c) Venn diagram and heat map showing dis-regulated genes across different passages of MSCs.