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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Transcriptome-aligned metabolic profiling by SERSome reflects biological changes following mesenchymal stem cells expansion

Fig. 4

Source data are available in the Source Data file

Consistent alterations in cellular processes. a GSEA analysis of up-regulated and down-regulated pathways in P6 MSCs compared to P2 MSCs (x-axis) and in P10 MSCs compared to P6 (y-axis), based on GO subset in AmiGO database. Normalized enrichment scores (NES) of GO terms are plotted. b Quantitative analysis of altered pathways across different passages of MSCs based on GSEA analysis. (c) Venn diagram and heat map showing dis-regulated genes across different passages of MSCs.

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