Fig. 5

Transcription factor analysis for vascularized pancreatic progenitors (vPP). (A) Volcano plot for differentially expressed TF genes of endoderm and mesoderm co-differentiation from Optimized Protocol compared to control protocol (Chen’s Protocol) on day 3. (B) Volcano plot for differentially expressed TF genes in vPP Protocol compared to PP from Chen’s protocol on day 10. (C) GO enrichment and gene correlation analysis of up-regulated differentially expressed TF genes associated with mesoderm development and vasculogenesis on day 3. (D) GO enrichment and gene correlation analysis of up-regulated differentially expressed TF genes associated with mesoderm development and vasculogenesis on day 10