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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression

Fig. 2

OSCC-MSCs promote the proliferation and migration of OSCC cells in vitro. (A) Schematic drawing of OSCC cell lines (CAL27 and HSC3) co-cultured with GMSCs or OSCC-MSCs through indirect cell-cell contact. (B-C) CCK-8 assay was used to determine the proliferation of CAL27 and HSC3 after co-culturing with GMSCs or OSCC-MSCs, respectively. (D-E) EdU assay was used to determine the proliferation of CAL27 and HSC3 after co-culturing with GMSCs or OSCC-MSCs, respectively. Scale bar, 100 μm. (F-G) Scratch assay was performed to analyze the migration ability of CAL27 and HSC3 after co-culturing with GMSCs or OSCC-MSCs, respectively. Scale bar, 200 μm. (H-I) Transwell assay was performed to analyze the migration ability of CAL27 and HSC3 after co-culturing with GMSCs or OSCC-MSCs, respectively. Scale bar, 200 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512