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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression

Fig. 3

OSCC-MSCs promote OSCC tumor growth in vivo. (A) Representative images of xenografts from two groups (CAL27 + GMSCs or CAL27 + OSCC-MSCs). n = 5 tumors. (B) Tumor volumes were calculated in CAL27 + GMSCs and CAL27 + OSCC-MSCs groups. n = 5 tumors. (C) Tumor weights were calculated in CAL27 + GMSCs and CAL27 + OSCC-MSCs groups. n = 5 tumors. (D) Representative H&E and IHC staining of Ki67 (left panel) in CAL27 + GMSCs and CAL27 + OSCC-MSCs xenografts. The bar graph (right panel) shows the quantification of Ki67 staining in the xenografts. Scale bar, 100 μm. n = 5 tumors. Data are presented as median with interquartile range. (E) Representative images of xenografts from two groups (HSC3 + GMSCs or HSC3 + OSCC-MSCs, left panel). n = 5 tumors. (F) Tumor volumes were calculated in HSC3 + GMSCs and HSC3 + OSCC-MSCs groups. n = 5 tumors. (G) Tumor weights were calculated in HSC3 + GMSCs and HSC3 + OSCC-MSCs groups. n = 5 tumors. (H) Representative H&E and IHC staining of Ki67 (left panel) in HSC3 + GMSCs and HSC3 + OSCC-MSCs xenografts. The bar graph (right panel) shows the quantification of Ki67 staining in the xenografts. Scale bar, 100 μm. n = 5 tumors. Data are presented as median with interquartile range

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