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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Semaphorin-4D signaling in recruiting dental stem cells for vascular stabilization

Fig. 2

Representative images of immunofluorescent staining to demonstrate the mural cell-like role of SHED. A, B Representative images of immunofluorescent stained sections for NG2 or PDGFR-β and CD31 at day 7. The arrows indicate that the vessels formed by CD31 + HUVECs were supported by SM22α + SHED. The white triangles indicate the vessels without SM22α+SHED support. * marks the vessel lumens. Scale bar = 50 μm. C Triple immunofluorescent staining for CD31, SM22α, and Collagen IV of Matrigel plug sections at day 7. The arrows indicate that vascular lumens lined by CD31+HUVECs were supported by SM22α+SHED on the abluminal surface and embedded within the collagen IV + basement membrane (pink). The white triangles indicate the vessels without SM22α+SHED support. * marks the vessel lumens, scale bar = 20 μm

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