Skip to main content
Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils

Fig. 8

hMSCs intervention facilitates the reprogramming of N2 type neutrophils through the PPAR-γ/STAT6/SOCS1 signaling pathway. A: qPCR to detect the expression levels of NE and MPO after hMSC-L treatment. B: qPCR to detect the expression levels of TGF-β and IL-10 after hMSC-L treatment. C: qPCR to detect the expression levels of NE and MPO after hMSC-M treatment. D: qPCR to detect the expression levels of TGF-β and IL-10 after hMSC-M treatment. E: ELISA to detect the expression levels of TGF-β and IL-10 after hMSC-L treatment. F: ELISA to detect the expression levels of TGF-β and IL-10 after hMSC-M treatment. n = 4, versus control *P < 0.05, **P < 0.01, ***P < 0.001. versus PMA #P < 0.05, ##P < 0.01, ###P < 0.001. versus hMSC-L/M $P < 0.01, $$P < 0.01, $$$P < 0.001

Back to article page