Circadian rhythms in stem cells and their therapeutic potential

Table 1 Negative evidence for circadian rhythm in stem cells

Species	Cell line	Passage	Indicators	References
Human	ESCs	Not specify	No circadian bioluminescence oscillations of clock genes	[14, 15]
	iPSCs	Not specify	Loss of circadian oscillations after dedifferentiation	[14]
	BM-MSCs	3–5	No circadian bioluminescence oscillations of clock genes	[44]
Mouse	ESCs	< 10, primary	No circadian bioluminescence oscillations of clock genes	[13, 45]
	iPSCs	Not specify	Loss of circadian oscillations after dedifferentiation	[13]
	NSCs	Primary	Non-rhythmic/ultradian bioluminescence oscillations of clock genes, turn into circadian rhythm after differentiation	[46]

ISSN: 1757-6512