Fig. 1

Establishment of NMOSD model. (A) Schematic diagram and experimental procedures for NMOSD model. (B) Clinical scores of EAE and NMOSD mice (n = 3 in each group). (C) Immunofluorescence of AQP4 (red) and GFAP (green) in the spinal cord from EAE and NMOSD mice. Cell nuclei are labeled by DAPI staining (blue). Scale bar 200 μm. White arrow: loss area of AQP4 and GFAP. (data = mean ± SEM, ns represents no significant difference between the two groups)