Fig. 3
From: Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalk
Identification of a novel RGC-protective factor, SCGF-β. A-B A significantly enhanced concentration of SCGF-β was detected in the RGC-iPSC-conditioned medium via multiplexed antibody-based assays and confirmed by ELISA. C A significantly greater RGC viability was observed in RGCs treated with 10 ng/mL SCGF-β after 5 days in vitro. D When CLEC11A (SCGF encoding gene) was knocked out in iPSCs, the RGC survival-promoting effect of iPSC coculture was depleted. *P < 0.05. Error bar denotes SD