Fig. 4

Immunomodulatory effect of DW treatment on IL-10, TGF-β, IL-17A expression and on the autoantibodies secretion. Bar graph showing the concentration of A IL‐10 cytokines (n = 12), B TGF-β (n = 12) and the relative expression of C IL-10 (n = 5), D IL-17A gene expression (n = 6) in Dex drug, DW and W treated PBMC’s with that of non-treated cells (lupus). DW treatment significantly suppressed the E anti-dsDNA F anti-ENA autoantibody levels in the supernatant as compared to that in lupus (non-treated cells). The bar graphs data represent mean of 6 patients’ sample. All values are represented as mean ± SD. non-significant (ns) p > 0.05, ***P < 0.001 and ****P < 0.0001, One-way ANOVA