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Table 3 A summary of the effects of both treatments on the primary parameters

From: The inconclusive superiority debate of allogeneic versus autologous MSCs in treating patients with HFrEF: a systematic review and meta-analysis of RCTs

Summary of effect sizes

Parameter\Source

AutoMSCs

 

 AlloMSCs

 

Comparison Results

 

Result

95% CI

Result

95% CI

 

MACE

0.90 RR

0.63–1.30

1.06 RR

0.87–1.29

Safer trend with AutoMSCs treatment

LVEF

2.17%

− 1.33–5.67

0.86%

− 1.21–2.94

Non-significant difference between groups, with a trend of superior efficacy with AutoMSCs treatment

6-MWD

31.17 m

− 8.91–71.25

31.88 m

5.03–58.74

Significant improvement with AlloMSCs treatment compared to non-significant improvement with AutoMSCs treatment