Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Transplantation of gastric epithelial mitochondria into human gastric cancer cells inhibits tumor growth and enhances chemosensitivity by reducing cancer stemness and modulating gastric cancer metabolism

Fig. 5

Pretreatment of epithelial mitochondria into gastric cancer cells suppressed tumor growth in a mouse tumor xenograft model. (A) Experimental design and flowchart of the mouse xenograft model and mitochondrial treatment. AGS cells were pretreated with GES-1 mitochondria for 24 h before injection. (B) Schematic of the gastric cancer xenografts in each group. (C) Body weights of mice in each group. (D) Tumor growth curves of each group. (E) Gastric tumors harvested from each group. (F) Representative images of hematoxylin and eosin and IHC staining of Ki-67 and GRP78 in each group. (G). Representative IHC analysis of ki-67 staining in each group. (H) Representative IHC analysis of GRP78 in each group. The data are presented as the means ± SEMs; n ≥ 3 for independent experiments; two-tailed Student’s t test: **p < 0.01 and ***p < 0.005

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512