Fig. 5

SVF-EVs enhanced the volume retention rate of grafts in animal test. Macroscopic images of the dermal particle grafts mixed with 0 or 40 ng/mL SVF-EVs after subcutaneous transplanted in nude mice for (A) 4 weeks and (B) 6 weeks. The quantitative analysis of (C) volume and (D) wet weight of subcutaneous grafts after transplanted for 4 and 6 weeks. (n = 4, *: p < 0.05, n.s: no significance, statistical methods: Student’s t test)