Fig. 5

thMSC-EVs’ effect in gene expression levels of differentiated NEC organoids.Bar graph representation of intestinal organoid marker gene expression levels analyzed using RT-qPCR. n = 4 and 4 in the NEC and NEC + thEV groups, respectively. Data are presented as mean ± SEM. *, p < 0.01 vs. NEC. The Mann–Whitney test was used in the analysis. CON, normal control; NEC, necrotizing enterocolitis control group; NEC + thEV, thMSC-EVs treated NEC group