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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Preclinical study of engineering MSCs promoting diabetic wound healing and other inflammatory diseases through M2 polarization

Fig. 6

MSCs-3IL accelerated the wound healing of STZ-induced diabetic mice. (A) Experimental setup illustrating the creation of a full-thickness skin defect model in STZ-induced diabetic mice and the treatment protocol using PBS, MSCs-V, MSCs-3IL, or MSCs-3IL-3d. (B) Representative images illustrating the progression of wound healing in diabetic mice treated with PBS, MSCs-V, MSCs-3IL, or MSCs-3IL-3d over 14 days. (C) Schematic diagram illustrating the stages of wound healing and closure over the 14 days. (D) Quantification of the wound closure area at different time points (days), with n ≥ 5 mice per group. (E) Survival rate comparison among the different treatment groups of diabetic mice throughout the experiment

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Stem Cell Research & Therapy

ISSN: 1757-6512