Fig. 1
From: Modeling of lung organoid-based fibrosis for testing the sensitivity of anti-fibrotic drugs
Self-assemble of the LOFs. A Microscope photography of the lung organoids and their morphological characteristics. Immunohistochemical staining of lung organoids for CK7, vimentin, desmin and a-SMA, showing that the lung organoids consisted of the CK7-positive cells. B Microscope photography of the fibroblasts and their morphological characteristics. Immunofluorescent staining for vimentin and a-SMA. C Microscope photography of the LOFs, showing the different shapes of the LOFs that formed in the C–F and O–F model