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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Hepatic progenitor cells reprogrammed from mouse fibroblasts repopulate hepatocytes in Wilson’s disease mice

Fig. 6

Transplantation of iHPCs downregulated the transcription of inflammatory cytokines and reduced the percentages of CD8+ T lymphocytes and natural killer cells among nonparenchymal cells in WD mice. Representative flow cytometry data and statistical analysis of the percentages of CD11c+GR1− dendritic cells (A), CD3+CD8+ T lymphocytes (B), and CD3-NK1.1+ natural killer cells (C) among liver-infiltrating CD45+ immune cells. (D) Real-time PCR analysis revealed the relative transcription levels of Tnfα, Ifnγ, IL-1α, IL-1β, and IL-6 in the liver

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Stem Cell Research & Therapy

ISSN: 1757-6512