Fig. 3

Peripheral blood HSPC concentrations (cells/µL) across 18 timepoints in all participants pooled (N = 18) (A) and then stratified by age (old, N = 9 vs. young, N = 9) for peak HSPC concentrations (B) total area under the curve (cells/µL x minutes) (C) average HSPC concentration (D) and HSPC dose (cells per kilogram of body mass) (E) in REST (grey circles and bars), MIIE (blue circles and bars) and HIIE (red circles and bars). Values are mean ± SD. * indicates significant differences between trials: *p < 0.05. Pairwise comparisons are not included on panel A