Fig. 2

Transcriptome analysis reveals gene enrichment heatmaps between AF- and UC-MSCs. A correlation heatmap of Euclidean distance scores of normalized genes counts on all three amniotic fluid samples and all four umbilical cord samples A. Dendrograms show hierarchical clustering results, and the ColorBrewer Blues scale show the similarities between AF-MSC and UC-MSC samples. A principal component analysis plot of all three amniotic fluid samples and all four umbilical cord samples B. The PCA plot shows the uniqueness in the sample groups. Volcano plot displaying the all differentially expressed genes between AF- and UC-MSCs C. Volcano plot shows the magnitude of change (log fold change) versus P adjusted < 0.05. Red markers indicate significantly upregulated genes and blue markers indicate significantly down-regulated genes (< 0.05). Grey markers indicate genes where Padj > 0.05. Leading edge analysis heatmap on pathways of interest D. Red boxes represent highly enriched genes per the respective pathway. Pink boxes represent weaker yet present enrichment per respective pathway