Table 2 Summary of donor characteristics, injection concentrations, and post-freeze viability for DNS-ONS and CRS-ONS
Donor category | Age (years) | Gender | 1st Injection (cells/mice) | 2nd Injection (cells/mice) | 3rd Injection (cells/mice) | 4th Injection (cells/mice) | Cell concentration (pre-freeze, cells/ml) | Cell concentration (post-freeze, cells/ml) | Viability (%) |
|---|---|---|---|---|---|---|---|---|---|
DNS-ONS | 27 | F | 5.1 × 106 | 4.8 × 106 | 4.5 × 106 | 5.3 × 106 | 3.0 × 107 | 1.7 × 107 | 56 |
38 | M | 4.5 × 106 | 4.5 × 106 | 5.7 × 106 | 5.0 × 106 | 4.4 × 107 | 3.6 × 107 | 82 | |
29 | M | 4.8 × 106 | 5.0 × 106 | 4.5 × 106 | 5.8 × 106 | 4.5 × 107 | 4.0 × 107 | 89 | |
31 | F | 4.8 × 106 | 5.1 × 106 | 5.3 × 106 | 5.5 × 106 | 4.1 × 107 | 4.1 × 107 | 99 | |
36 | F | 5.4 × 106 | 5.4 × 106 | 4.6 × 106 | 5.1 × 106 | 4.6 × 107 | 4.0 × 107 | 87 | |
CRS-ONS | 72 | M | 4.8 × 106 | 5.0 × 106 | 4.5 × 106 | 5.0 × 106 | 4.2 × 107 | 4.1 × 107 | 98 |
61 | M | 4.5 × 106 | 4.7 × 106 | 5.6 × 106 | 5.0 × 106 | 6.6 × 107 | 4.8 × 107 | 73 | |
55 | F | 5.0 × 106 | 5.6 × 106 | 5.0 × 106 | 5.6 × 106 | 6.6 × 107 | 4.2 × 107 | 63 | |
49 | M | 5.6 × 106 | 4.6 × 106 | 5.0 × 106 | 5.6 × 106 | 9.6 × 107 | 5.2 × 107 | 54 | |
64 | M | 5.3 × 106 | 5.5 × 106 | 5.6 × 106 | 4.7 × 106 | 4.5 × 107 | 4.3 × 107 | 90 |