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Table 3 Percentage of variance accounted for in sample models for the total observed proteins, wherein residuals refer to unexplained variance. *MMP: matrix metalloproteinase; AO: antioxidant

From: Quantifying extracellular vesicle heterogeneity: the effect of process conditions on protein cargo for skin therapy

 

All

MSC

Factor

Total (%)

Immune (%)

MMP (%)

AO (%)

Total (%)

Immune (%)

MMP(%)

AO (%)

EV Source

–

–

16.0

–

1.7

–

–

–

Ionization

0.9

–

6.5

–

–

4.9

13.7

0.8

Isolation

18.7

–

–

2.5

34.1

34.5

–

46.6

Medium

5.6

49.5

12.4

47.5

2.1

–

10.1

–

Search Algorithm

11.3

1.6

–

–

0.7

12.7

–

13.0

Residual

63.6

48.9

65.2

49.5

61.3

47.9

76.3

39.6