Fig. 3
From: Erythropoietin delivery through kidney organoids engineered with an episomal DNA vector
EPO affects kidney organoid differentiation. A. mRNA expression of PODXL, Villin-1, E-cadherin and PECAM-1 in control organoids and EPO + organoids. Data are shown as median (IQR). Welch’s t-test was used to test for significance; n = 14 for control, n = 13 for EPO+. B. Immunohistochemical staining of PODXL, Villin-1, E-cadherin and PECAM-1 in control organoids and EPO + organoids. C. Quantification of PODXL, Villin-1, E-cadherin and PECAM-1 immunohistochemistry in control organoids and EPO + organoids. Data are shown as mean ± SD. Significance was tested by Mann-Whitney test; PODXL: n = 20 for control, n = 20 for EPO+; Villin-1: n = 22 for control, n = 20 for EPO+; E-cadherin: n = 22 for control, n = 17 for EPO+; PECAM-1: n = 22 for control, n = 20 for EPO+. **: p < 0.01, ***: p < 0.001