Fig. 6
From: Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway
A Effect of MSC-EVs treatments on gene expression of tissue factor (TF) in lung tissues from different experimental groups. Data are expressed as mean ± SE. ****significant compared to Control at p < 0.0001 and ## significant compared to COVID- 19 group at p < 0.01. B Representative photomicrographs from PAI-1 immune stained lung sections showing a Control group: negative immune reaction. b Covid group: with intense immune reaction in consolidated lung tissue (curved arrow). c MSCs-EVs group: negative immune reaction. d Graph showing Allred score for PAI-1 expression. Data are expressed as mean ± SEM.***p < 0.001 versus control, ###p < 0.001 versus COVID group. Allred index (0–1 = negative, 2–3 = mild, 4–6 = moderate, and 7–8 = strongly positive)