Table 1 Clastokines involved in bone remodeling
Clastokine | Function | References |
|---|---|---|
Complement component 3a (C3a) | Stimulates bone formation | |
Wnt Family Member 5 A (WNT5 A) | Stimulates bone formation | [58] |
Slit Guidance Ligand 3 (SLIT3) | Stimulates bone formation | [59] |
Cardiotrophin- 1 (CT- 1) | Stimulates bone formation | [49] |
Leukemia inhibitory factor (LIF) | Stimulates bone formation | |
Tartrate-resistant acid phosphatase (TRAcP) | Stimulates bone formation | |
Sphingosine 1-phosphate (S1P) | Stimulates bone formation | |
Bone morphogenetic protein 6 (BMP6) | Stimulates bone formation | [49] |
Int/wingless 10b (Wnt10b) | Stimulates bone formation | [49] |
Hepatocyte growth factor (HGF) | Stimulates bone formation | [48] |
Collagen triple helix repeat containing 1 (CTHRC1) | Stimulates bone formation | [48] |
Platelet-derived growth factor BB (PDGF BB) | Inhibits bone formation | [56] |
Sclerostin (SOST) | Inhibits bone formation | [63] |
Semaphorin 4D (SEMA4D) | Inhibits bone formation |