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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: Biomanufacturing and lipidomics analysis of extracellular vesicles secreted by human blood vessel organoids in a vertical wheel bioreactor

Fig. 9

In vitro functional assays in an iBVO senescence model for EV therapeutic evaluation. (A) (i) ROS reduction relative to cells induced with D-galactose. (ii) Representative ROS images; (B) Relative cell proliferation compared to cells induced with D-galactose. (ii) Representative cell proliferation images; (C) (i) Relative mitochondrial activity compared to cells induced with D-galactose. (ii) Representative mitochondrial activity images. Scale bar: 100 μm. N = 3, *: p < 0.05, **: p < 0.01, ***: p < 0.001. N.S.: not significant

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