Fig. 4
From: Human platelet lysate produced from leukoreduction filter contents enables sufficient MSC growth
Cell expansion potential for small and large-scale production of f-hPL. (A) The MSCs expansion capacity was assessed using both small-scale (approximately 50 filters) and large-scale (approximately 150 filters) production of f-hPL. Small-scale f-hPL demonstrated significantly higher cell expansion potential compared to commercial platelet lysate (PL) and fetal bovine serum (FBS). (B) Similarly, large-scale f-hPL exhibited significantly greater cell expansion capacity compared to FBS. (C) Microscopic analysis of MSCs expanded with large-scale f-hPL and FBS revealed the characteristic spindle-shaped morphology of MSCs. Bar = 500 μm