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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Effects of 3D-printed exosome-functionalized brain acellular matrix hydrogel on neuroinflammation in rats following cerebral hemorrhage

Fig. 4

dECM@exo inhibits astrocyte apoptosis. (A) Representative images of JC-1 staining. (B) Statistical plot of astrocyte JC-1 fluorescence (red/green) ratio (n = 3). (C) Representative images of apoptosis by flow cytometry. (D) Statistical diagram of astrocyte apoptosis (n = 3). (E-H) ELISA analysis of MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in astrocyte supernatants. Scale bars: A 50 μm. Data were expressed as mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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