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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Effects of 3D-printed exosome-functionalized brain acellular matrix hydrogel on neuroinflammation in rats following cerebral hemorrhage

Fig. 6

dECM@exo reduces the inflammatory response after ICH. (A) Corner test (n = 12). (B) Forelimb placement test (n = 12). (C) Bederson and (D) Longa scores were performed from day 1 to day 14 after ICH to evaluate the recovery of neurological function (n = 12). (E) Total leukocyte count in different groups (n = 12). (F-H) ELISA method was used to detect the concentrations of IL-1β, TNF-α and IL-10 in serum (n = 4). (I) Western blot of TLR4 and NF-κB/P65, p-P65. (J) Statistical analysis of TLR4 (n = 3). (K) Statistical analysis of TLR4 mRNA (n = 3). Data were expressed as mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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