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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Bone marrow mesenchymal stem cells transport connexin43 via tunneling nanotubes to alleviate isopreterenol-induced myocardial hypertrophy

Fig. 6

Effect of ISO on the transfer of Cx43 from MSCs to CMs. (A) Transfecting Lentivirus (LV)-mCherry-Cx43 into MSCs (red) for 7 days, and then co-culturing with CMFDA-labeled CMs (green) for 24 h. CMs (green) containing LV-mCherry-Cx43 (red) were detected by flow cytometry regardless ISO treatment. N = 3. (B) Comparison of the percentage of CMFDA-labeled CMs (green) containing Lv-Cx43-mCherry(red) in all CMFDA-labeled CMs (green) under co-culture conditions with and without ISO stimulation. N = 3, Data are shown as the mean ± S.E.M. * P < 0.05 vs Ctrl

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Stem Cell Research & Therapy

ISSN: 1757-6512