Fig. 7
The STAT3 signaling pathway mediates hUC-MSC-dependent chemokine regulation. A Changes in STAT3 signaling pathway activity in mouse skin following hUC-MSC treatment. B Western blot analysis of changes in STAT3 signaling pathway activity following treatment with exosomes. Full-length blots are presented in Supplementary Figure. C Effect of Stattic on HaCaT cell viability. D qRT-PCR analysis of HaCaT cell-related chemokine mRNA expression following treatment with Stattic (10 μM)