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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Puerarin relives inflammation, bone destruction and facilitates osteogenic differentiation in periodontitis by enhancing mitochondrial autophagy via activating mitochondrial Mitofusin 2

Fig. 1

Pue treatment improved PD in mice. (A) Establishment of the mouse models of PD. (B-C) Sulcus bleeding index and tooth mobility analysis in mice. n = 6. (D-E) Micro-CT images and analysis of CEJ-ABC distance, BV/TV, Tb. N and Tb. Sp in mice. n = 6. (F) H&E staining of periapical tissues in mice was carried out to observe pathological changes. n = 3. (G-J) Immunohistochemistry of periapical tissues in mice was adopted to explore osteogenic differentiation capacity. n = 3. (K-M) Pro-inflammatory factors in periapical tissues of mice by ELISA. N = 6. (N) Expression of osteogenesis-related genes in periapical tissues of mice by qRT-PCR. n = 3. * P < 0.05. ** P < 0.01. *** P < 0.001. The “ns” symbol represented no obvious difference

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Stem Cell Research & Therapy

ISSN: 1757-6512